Endocrine Abstracts

Introduction: Apart from being individually associated with cardiometabolic health, Vitamin D and growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis are reported to interplay, with a positive correlation between IGF-1 and 25-hydroxyvitamin D (25(OH)D). These findings raise questions about the role of vitamin D for the adverse cardiovascular (CV) risk profile in hyposomatotropism. Thus, the aim of our study was to investigate the association between 25(OH)D and metabol...

Introduction: Vitamin D and growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis are reported to interplay at both endocrine and paracrine levels, with a positive correlation between IGF-1 and 25-hydroxyvitamin D (25(OH)D) in healthy subjects. Hyposomatotropism is among the conditions predisposing to lower vitamin D status due to several direct and indirect mechanisms. Thus, the aim of our study was to evaluate vitamin D status in a representative sample of adults with ...

Metabolic abnormalities in adult GH deficiency (AGHD) determine its significance as a disease associated with increased cardiovascular risk. However, recent contradictory data about the long-term beneficial effects of GH replacement, especially on cardiovascular risk, provoked some further analysis of its contributory factors.Aim of the study: To identify the individual risk factors of metabolic syndrome (MS) in AGHD and to compare the prevalence and the...